Human Caspases: Activation, Specificity, and Regulation
نویسندگان
چکیده
منابع مشابه
Minireview. Human Caspases: Activation, Specificity and Regulation
Caspases are intracellular proteases that propagate programmed cell death, proliferation and inflammation. Activation of caspases occurs by a conserved mechanism subject to strict cellular regulation. Once activated by a specific stimulus, caspases execute limited proteolysis of downstream substrates to trigger a cascade of events that culminates in the desired biological response. Much has bee...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2009
ISSN: 0021-9258
DOI: 10.1074/jbc.r800084200